Modern approaches in treatment of helicobacteriosis in patients with peptic ulcer

Peptic ulcer is a chronic recurrent disease, accompanied by alternating periods of exacerbation and remission, its main feature the formation an in wall stomach (or) duodenum, penetrating – this difference from superficial damage to mucous membrane (erosions) into submucosal layer. The etiology appearance Helicobacter pylori (H. pylori) falling favorable conditions with weakened microfl presence aggressive factors environment. In pathogenesis peptic thinning gastrointestinal mucosa violation compensation mechanisms at local level are paramount importance. An important role diagnosis given carefully collected anamnesis complaints patient, supplemented physical examinations, laboratory instrumental examination methods. treatment patients based on modern methods treatment, where latest drugs proven effi well-proven clinical practice used, consistent international recommendations Maastricht V / Florence Consensus, anti-helicobacter therapy mandatory for gastritis. Currently, still combination antimicrobial agents (amoxicillin, clarithromycin, metronidazole), antisecretory (proton pump inhibitors). Standard triple therapy, which includes PPIs two antibiotics (clarithromycin amoxicillin/metronidazole) widely used as main-line regimen infection. addition, concomitant use alternative medicine emergence adaptive or synergistic effects against H.